1990 American College of Rheumatology Criteria for Wegener’s Granulomatosis (WG).

Note: WG is now known as Granulomatosis with Polyangiitis (GPA).

  • Nasal or oral inflammation: painless or painful oral ulcers or purulent or bloody nasal discharge
  • Abnormal chest radiograph: the presence of nodules, fixed infiltrates or cavities
  • Urinary sediment: microhematuria (>  5 red blood cells per high power field) or red cell casts in urine sediment
  • Granulomatous inflammation on biopsy: granulomatous inflammation within the wall of an artery or in the perivascular or extravascular area (artery or arteriole)


≥ 2 of the above 4 criteria are required for classification as GPA.  Sensitivity 88.2%, specificity 92.0%.


Leavitt et al.  The American College of Rheumatology 1990 criteria.