1990 American College of Rheumatology Criteria for Wegener’s Granulomatosis (WG).
Note: WG is now known as Granulomatosis with Polyangitis (GPA)
- Nasal or oral inflammation: painless or painful oral ulcers or purulent or bloody nasal discharge
- Abnormal chest radiograph: presence of nodules, fixed infiltrates or cavities
- Urinary sediment: microhematuria (> 5 red blood cells per high power field) or red cell casts in urine sediment
- Granulmatous inflammation on biopsy: granulomatous inflammation within the wall of an artery or in the perivascular or extravascular area (artery or arteriole)
Requirements: ≥ 2 of the above 4 criteria are required for classification as GPA. Sensitivity 88.2%, specificity 92.0%.
Reference: Leavitt et al. The American College of Rheumatology 1990 criteria for the classification of Wegener’s Granulomatosis. Arthritis Rheum 1990;33:1101-7.