1990 American College of Rheumatology Classification Criteria for Giant Cell Arteritis
- Age of onset ≥50 years (symptoms or signs beginning at 50 years or older)
- New headache (new onset of or new type of localized pain in the head)
- Temporal artery abnormality£ (tenderness or decreased pulsation)
- Elevated ESR ≥ 50 mm/hr (by the Westergren method)
- Abnormal artery biopsy (vasculitis characterized by predominance of mononuclear cell infiltrates or granulomatous inflammation with multinucleated giant cells)
Requirements: ≥ 3 of the above criteria are required for classification as Giant Cell Arteritis. Sensitivity 93.5%, specificity 91.2%.
Reference: Hunder et al. The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 1990;33(8):1122-8.
- £In clinical practice, temporal artery abnormalities include tenderness, decreased or absent pulsation, induration (cord-like) and nodularity.
- GCA was previously, and less-appropriately, known as Temporal Arteritis. Inflammation can involve other intracranial and extracranial arteries.